Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912133 | 0.94 | CYP3A4 (0.54) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL3700781 | 0.78 | MEN1 (0.50) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL9271155 | 0.75 | CYP3A4 (0.50) | CYP3A4MEN1KMT2AGLAALDH1A1 | |
| SCHEMBL563659 | 0.74 | ALOX15 (0.54) | CYP3A4MEN1KMT2AGLAALDH1A1 | |
| SCHEMBL6174115 | 0.74 | HSD17B3 (0.51) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL5715985 | 0.74 | KMT2A (0.48) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL9265255 | 0.74 | KMT2A (0.48) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL2316707 | 0.73 | CYP3A4 (0.48) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL30302271 | 0.73 | CYP3A4 (0.48) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL6911155 | 0.73 | MAPT (0.56) | CYP3A4MEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1749252-B | Compounds useful to treat retroviral infections | PHARMACIA & UPJOHN CO LLC (US) | 2011-06-08 | — | — | CN | disclosed |
| CN-1329378-C | Compounds for the treatment of retroviral infections | PHARMACIA & UPJOHN CO LLC (US) | 2007-08-01 | — | — | CN | disclosed |
| CN-1749252-A | Compounds useful to treat retroviral infections | PHARMACIA & UPJOHN CO LLC (US) | 2006-03-22 | — | — | CN | disclosed |
| CN-1539825-A | Compounds for the treatment of retroviral infections | �������Ŷ���Լ��������˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1154642-C | Compounds for the treatment of retroviral infections | �������Ŷ���Լ��������˾ | 2004-06-23 | — | — | CN | disclosed |
| CN-1150424-A | Compounds for the treatment of retroviral infections | UPJOHN CO (US) | 1997-05-21 | — | — | CN | disclosed |