Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267917 | 0.95 | PTGS2 (0.55) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14352870 | 0.86 | PTGS2 (0.48) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14352868 | 0.86 | PTGS2 (0.48) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3976286 | 0.85 | PTGS2 (0.50) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL12646489 | 0.84 | GAA (0.59) | MAPTALDH1A1SMN1; SMN2PTGER4HPGD | |
| SCHEMBL2116437 | 0.84 | PTGS2 (0.66) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6163614 | 0.83 | MAPT (0.69) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10119179 | 0.82 | PTGS2 (0.57) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13918253 | 0.81 | FFAR1 (0.61) | MAPTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3973631 | 0.81 | PTGS2 (0.53) | PTGS2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029155-A1 | NOVEL ANTITUMOUR COMPOUNDS WITH ANTIMITOTIC ACTIVITY | PHARMACIA AB (SE) | 1995-11-02 | — | — | WO | disclosed |