Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 3/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | FABP2 | P12104 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261213 | 0.79 | CLCN2 (0.56) | CLCN2NOTUMPTGS2MEN1MAPK1 | |
| SCHEMBL9260566 | 0.77 | HPGD (0.56) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL9265856 | 0.75 | CLCN2 (0.52) | CLCN2NOTUMPTGS2MEN1MAPK1 | |
| SCHEMBL9261411 | 0.75 | CLCN2 (0.55) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL9267093 | 0.75 | CLCN2 (0.52) | CLCN2NOTUMPTGS2MEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL9270389 | 0.75 | CLCN2 (0.49) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL9683614 | 0.75 | PTGS2 (0.51) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL7902075 | 0.75 | CLCN2 (0.57) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL9260755 | 0.75 | CLCN2 (0.57) | CLCN2NOTUMPTGS2MEN1MAPK1 | |
| SCHEMBL6190856 | 0.73 | NOTUM (0.54) | NOTUMMEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5462952-A | Have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase | WARNER-LAMBERT COMPANY (US) | 1995-10-31 | — | — | US | claimed |
| EP-0401857-A2 | Fenamate 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1990-12-12 | — | — | EP | claimed |
| US-5462952-A | Have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase | WARNER-LAMBERT COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0401857-A2 | Fenamate 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1990-12-12 | — | — | EP | disclosed |