Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.53 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265505 | 1.00 | KCNA5 (0.53) | KCNA5ABCC9MEN1KMT2ANPC1 | |
| SCHEMBL9265483 | 1.00 | KCNA5 (0.53) | KCNA5ABCC9MEN1KMT2ANPC1 | |
| SCHEMBL7722209 | 0.85 | ABCC9 (0.64) | ABCC9 | |
| SCHEMBL8343023 | 0.85 | ABCC9 (0.64) | ABCC9 | |
| SCHEMBL3303489 | 0.85 | ABCC9 (0.64) | ABCC9 | |
| SCHEMBL8343026 | 0.85 | ABCC9 (0.64) | ABCC9 | |
| SCHEMBL16027515 | 0.85 | ABCC9 (0.56) | ABCC9 | |
| SCHEMBL10886662 | 0.84 | ABCC9 (0.58) | ABCC9 | |
| SCHEMBL9689218 | 0.84 | ABCC9 (0.50) | KCNA5ABCC9 | |
| SCHEMBL9689208 | 0.84 | ABCC9 (0.50) | KCNA5ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462761-A2 | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E.R. SQUIBB & SONS, INC. (US) | 1991-12-27 | — | — | EP | claimed |
| US-5466817-A | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E.R. SQUIBB & SONS, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5276168-A | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E. R. SQUIBB & SONS, INC. (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0462761-A2 | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E.R. SQUIBB & SONS, INC. (US) | 1991-12-27 | — | — | EP | disclosed |