Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261614 | 1.00 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| Hydrochloric Acid SCHEMBL9268819 | 0.98 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| Hydrochloric Acid SCHEMBL9263385 | 0.98 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| Hydrochloric Acid SCHEMBL9257279 | 0.98 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL8114272 | 0.95 | CHRM2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL3853785 | 0.95 | CHRM2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL164422 | 0.95 | CHRM2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| Oxalic Acid SCHEMBL8104972 | 0.86 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| Oxalic Acid SCHEMBL8114514 | 0.86 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL9265217 | 0.86 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409946-A | Antiepileptic agent | ABBOTT LABORATORIES (US) | 1995-04-25 | — | — | US | disclosed |