Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088214 | 0.79 | SMN1; SMN2 (0.71) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL2880593 | 0.79 | NNMT (0.55) | ALDH1A1NNMTKMT2ACDC25BMEN1 | |
| SCHEMBL9261247 | 0.79 | KDM4E (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL9268220 | 0.78 | NNMT (0.58) | ALDH1A1NNMTKMT2AMEN1MAPT | |
| SCHEMBL18228074 | 0.76 | NNMT (0.72) | ALDH1A1SMN1; SMN2NNMTKMT2AMEN1 | |
| SCHEMBL31331689 | 0.76 | HTT (0.63) | ALDH1A1SMN1; SMN2KMT2AMAPTHTT | |
| SCHEMBL23319565 | 0.75 | ERN1 (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL7262531 | 0.74 | GAA (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL13720914 | 0.74 | TSHR (0.55) | ALDH1A1SMN1; SMN2NNMTKMT2ACDC25B | |
| SCHEMBL4268078 | 0.74 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391314-A | Heat resistance; cold resistance;, storage stability | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-02-21 | — | — | US | claimed |
| EP-0457597-B1 | Electroviscous fluid composition | SHINETSU CHEMICAL CO (JP) | 1994-08-03 | — | — | EP | claimed |
| EP-0457597-A1 | Electroviscous fluid composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1991-11-21 | — | — | EP | claimed |
| US-4135943-A | ADSORBER DISPERSED IN CROSSLINKED POLYMERIC MATRIX | TOYO JOZO COMPANY, LTD. (JP) | 1979-01-23 | — | — | US | claimed |
| US-5478933-A | Benzodiazepine derivatives and their use as antagonists of cholecystokinin and/or gastrin receptors | MERCK SHARPE & DOHME LTD. (GB) | 1995-12-26 | — | — | US | disclosed |
| US-5391314-A | Heat resistance; cold resistance;, storage stability | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0457597-B1 | Electroviscous fluid composition | SHINETSU CHEMICAL CO (JP) | 1994-08-03 | — | — | EP | disclosed |
| WO-1993007131-A1 | BENZODIAZEPINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF CHOLECYSTOKININ AND/OR GASTRIN RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |
| EP-0457597-A1 | Electroviscous fluid composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1991-11-21 | — | — | EP | disclosed |
| US-4135943-A | ADSORBER DISPERSED IN CROSSLINKED POLYMERIC MATRIX | TOYO JOZO COMPANY, LTD. (JP) | 1979-01-23 | — | — | US | disclosed |