Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.63 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.63 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.63 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.57 |
| ▸ | LTA4H | P09960 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262310 | 0.90 | TAAR1 (0.62) | TAAR1NPC1RAB9AGAAPLAAT3 | |
| SCHEMBL9271074 | 0.88 | FAAH (0.61) | TAAR1NPC1RAB9AGAAPLAAT3 | |
| SCHEMBL16552390 | 0.84 | EPHX2 (0.64) | TAAR1NPC1RAB9AGAAPLAAT3 | |
| SCHEMBL9263805 | 0.84 | NPC1 (0.67) | TAAR1NPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL4850675 | 0.84 | TAAR1 (0.66) | TAAR1NPC1RAB9AGAAEPHX2 | |
| SCHEMBL30941666 | 0.82 | EPHX2 (0.69) | PLAAT3PLAAT5PLAAT2PLAAT4EPHX2 | |
| SCHEMBL14470497 | 0.82 | TAAR1 (0.68) | TAAR1NPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL16939921 | 0.82 | HSD17B10 (0.51) | TAAR1NPC1RAB9AGAALTA4H | |
| SCHEMBL28915067 | 0.81 | TAAR1 (0.67) | TAAR1NPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL13055389 | 0.81 | TAAR1 (0.60) | TAAR1NPC1RAB9AGAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391571-A | Cholesterol ester hydrolase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-02-21 | — | — | US | claimed |
| US-5391571-A | Cholesterol ester hydrolase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0428385-A1 | Cholesterol ester hydrolase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |