Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270865 | 0.95 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3AHSD17B1 | |
| SCHEMBL9270861 | 0.95 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3AHSD17B1 | |
| SCHEMBL9270858 | 0.95 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3AHSD17B1 | |
| SCHEMBL9270854 | 0.95 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3AHSD17B1 | |
| SCHEMBL9617266 | 0.83 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3ALSS | |
| SCHEMBL13557301 | 0.83 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3ALSS | |
| SCHEMBL9179061 | 0.83 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3ALSS | |
| SCHEMBL9179048 | 0.83 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3ALSS | |
| SCHEMBL9179054 | 0.83 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3ALSS | |
| SCHEMBL9617265 | 0.83 | DRD2 (0.41) | DRD2SLC2A1SLC18A3HTR3ALSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399689-A | Chlorophenylalkoxyalkyl compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0475254-B1 | Chlorophenyl-alkoxyalkyl-compounds | HOFFMANN LA ROCHE (CH) | 1994-12-28 | — | — | EP | disclosed |
| EP-0475254-A1 | Chlorophenyl-alkoxyalkyl-compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |