Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268159 | 1.00 | FFAR1 (0.46) | FFAR1RAB9ANPC1KMT2AGRM6 | |
| SCHEMBL9268939 | 0.88 | NPC1 (0.35) | FFAR1RAB9ANPC1KMT2AHPGD | |
| SCHEMBL9268942 | 0.88 | NPC1 (0.35) | FFAR1RAB9ANPC1KMT2AHPGD | |
| SCHEMBL9261832 | 0.87 | FFAR1 (0.38) | FFAR1RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL9261835 | 0.87 | FFAR1 (0.38) | FFAR1RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL9261268 | 0.86 | NPC1 (0.45) | RAB9ANPC1KMT2AHPGDALDH1A1 | |
| SCHEMBL9265407 | 0.86 | SMN1; SMN2 (0.45) | RAB9ANPC1KMT2AALDH1A1CTSK | |
| SCHEMBL9261261 | 0.86 | NPC1 (0.45) | RAB9ANPC1KMT2AHPGDALDH1A1 | |
| SCHEMBL9266729 | 0.86 | SMN1; SMN2 (0.38) | RAB9ANPC1KMT2AALDH1A1CTSK | |
| SCHEMBL9266726 | 0.86 | SMN1; SMN2 (0.38) | RAB9ANPC1KMT2AALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613463-A1 | DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION | G.D. SEARLE & CO. (US) | 1994-09-07 | — | — | EP | claimed |
| US-5272178-A | Compounds of cyclic phenolic thioethers which are useful in stimulating and inhibiting superoxide generation | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | claimed |
| WO-1993010087-A1 | DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | claimed |
| US-5476944-A | Inhibitors or stimulators of superoxide generation; may also inhibit cyclooxygenase and/or 5-lipoxygenase; useful in therapeutic or prophylactic treatment of disease conditions | G. D. SEARLE & CO. (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0613463-A1 | DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION | G.D. SEARLE & CO. (US) | 1994-09-07 | — | — | EP | disclosed |
| WO-1993010087-A1 | DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |