SCHEMBL9268185 — predicted protein targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	GABRG2	P18507	18/20	0.78

▸	GABRB3	P28472	18/20	0.78

▸	GABRA5	P31644	18/20	0.78

▸	GABRA1	P14867	1/20	0.54

▸	GABRA3	P34903	1/20	0.54

▸	GABRA6	Q16445	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9267475	0.89	GABRG2 (0.78)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL3574560	0.87	GABRG2 (1.00)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL9262174	0.86	GABRG2 (0.76)	GABRG2GABRB3GABRA5
SCHEMBL3571681	0.86	GABRG2 (0.76)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL9661308	0.85	GABRG2 (0.62)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL3570896	0.85	GABRG2 (0.74)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL9254253	0.84	GABRG2 (0.73)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL9661282	0.84	GABRG2 (0.73)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL3567727	0.83	GABRG2 (0.79)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL3570561	0.81	GABRG2 (0.69)	GABRG2GABRB3GABRA5GABRA1GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5387585-A	Treating epilepsy, anxiety, sleep disorders, schizophrnia, senile dementia	HOFFMANN-LA ROCHE INC. (US)	1995-02-07	—	—	US	disclosed