Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | HTR1B | P28222 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268676 | 0.87 | HTR1A (0.52) | HTR1AHTR1BDRD2HTR2A | |
| SCHEMBL9271964 | 0.86 | HTR1A (0.56) | HTR1AHTR1BDRD2HTR2A | |
| SCHEMBL9273260 | 0.85 | HTR1A (0.51) | HTR1AHTR1BDRD2HTR2A | |
| SCHEMBL9273354 | 0.85 | HTR1A (0.51) | HTR1AHTR1BDRD2HTR2A | |
| SCHEMBL9268057 | 0.84 | HTR1A (0.52) | HTR1AHTR1BDRD2HTR2A | |
| SCHEMBL9272215 | 0.83 | HTR1A (0.53) | HTR1AHTR1BDRD2HTR2ALTA4H | |
| SCHEMBL9271583 | 0.82 | HTR1A (0.52) | HTR1AHTR1BDRD2HTR2A | |
| SCHEMBL9265574 | 0.81 | HTR1A (0.47) | HTR1AHTR1BDRD2HTR2A | |
| SCHEMBL8557182 | 0.77 | HTR1A (0.74) | HTR1AHTR1BDRD2HTR2A | |
| SCHEMBL9265778 | 0.76 | HTR1A (0.68) | HTR1AHTR1BDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420150-A | Antidepressants and treatment of anxiety | GUILLAUMET GERALD (FR) | 1995-05-30 | — | — | US | disclosed |