Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211886 | 0.87 | OXER1 (0.53) | OXER1MAPTALDH1A1MEN1HTT | |
| SCHEMBL9273621 | 0.87 | OXER1 (0.53) | OXER1MAPTALDH1A1MEN1HTT | |
| SCHEMBL9267182 | 0.85 | OXER1 (0.52) | OXER1MAPTMGAMGAASI | |
| SCHEMBL8499141 | 0.82 | ALDH1A1 (0.46) | OXER1MAPTALDH1A1MEN1HTT | |
| SCHEMBL9271005 | 0.81 | PPARA (0.48) | OXER1MAPTALDH1A1MEN1HTT | |
| SCHEMBL9268276 | 0.81 | OXER1 (0.62) | OXER1MAPTALDH1A1MEN1HTT | |
| SCHEMBL15512501 | 0.81 | OXER1 (0.62) | OXER1MAPTALDH1A1MEN1HTT | |
| SCHEMBL17022468 | 0.80 | OXER1 (0.62) | OXER1MAPTALDH1A1MEN1HTT | |
| SCHEMBL9265201 | 0.79 | OXER1 (0.74) | OXER1MAPTALDH1A1MEN1HTT | |
| SCHEMBL9267825 | 0.78 | OXER1 (0.84) | OXER1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013266-A1 | ACYLPYRROLE-ALKANOIC ACIDS AND INDOLE-2-ALKANOIC ACIDS PLUS THEIR DERIVATIVES FOR USE AS INHIBITORS OF PHOSPHOLIPASE A¿2? | MERCKLE GMBH CHEM.-PHARM. FABRIK (DE) | 1995-05-18 | — | — | WO | disclosed |