Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 12/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267912 | 0.91 | STAT3 (0.61) | STAT3HTTTOP2ATOP2BGSK3B | |
| SCHEMBL1344898 | 0.90 | STAT3 (0.54) | STAT3HTTTOP2ATOP2BGSK3B | |
| SCHEMBL9273133 | 0.86 | STAT3 (0.49) | STAT3HTTTOP2ATOP2BGSK3B | |
| SCHEMBL9261876 | 0.84 | STAT3 (0.47) | STAT3HTTTOP2ATOP2BGSK3B | |
| SCHEMBL13483600 | 0.84 | STAT3 (0.52) | STAT3HTTTOP2ATOP2BGSK3B | |
| SCHEMBL9265456 | 0.84 | STAT3 (0.42) | STAT3HTTTOP2ATOP2BGSK3B | |
| SCHEMBL9264770 | 0.83 | GSK3B (0.57) | STAT3TOP2ATOP2BGSK3BCACNA1F | |
| SCHEMBL6880793 | 0.83 | GSK3B (0.50) | STAT3TOP2ATOP2BGSK3BCACNA1F | |
| SCHEMBL5704363 | 0.81 | GSK3B (0.51) | STAT3TOP2ATOP2BGSK3BCACNA1F | |
| SCHEMBL9688633 | 0.81 | CACNA1F (0.49) | STAT3TOP2ATOP2BGSK3BCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407932-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0393400-B1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KK (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5245037-A | Synthetic bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0393400-A1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-24 | — | — | EP | disclosed |