Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | EDNRB | P24530 | 6/20 | 0.51 |
| ▸ | EDNRA | P25101 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL9268612 | 0.98 | ALDH1A1 (0.55) | ALDH1A1POLBGAAMAPTEDNRB | |
| SCHEMBL9263398 | 0.90 | EDNRB (0.57) | EDNRBEDNRA | |
| SCHEMBL9267320 | 0.89 | EDNRB (0.54) | EDNRBEDNRA | |
| Potassium SCHEMBL9263403 | 0.88 | EDNRB (0.57) | EDNRBEDNRA | |
| SCHEMBL9272346 | 0.87 | EDNRA (0.60) | EDNRBEDNRA | |
| Potassium SCHEMBL9267325 | 0.87 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL8906488 | 0.87 | EDNRA (0.57) | EDNRBEDNRA | |
| Potassium SCHEMBL9272349 | 0.85 | EDNRA (0.60) | EDNRBEDNRA | |
| Potassium Ion SCHEMBL8907336 | 0.85 | EDNRA (0.53) | EDNRBEDNRA | |
| SCHEMBL9269338 | 0.85 | EDNRA (0.53) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003295-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | claimed |
| WO-1995003295-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |