Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102042 | 0.84 | MAPT (0.34) | ALDH1A1MAPTNPSR1TET2EGLN1 | |
| SCHEMBL7102045 | 0.84 | MAPT (0.34) | ALDH1A1MAPTNPSR1TET2EGLN1 | |
| SCHEMBL7171266 | 0.82 | MAPT (0.32) | ALDH1A1MAPTNPSR1TET2EGLN1 | |
| SCHEMBL7173968 | 0.82 | MAPT (0.32) | ALDH1A1MAPTNPSR1TET2EGLN1 | |
| SCHEMBL7172761 | 0.82 | MAPT (0.32) | ALDH1A1MAPTNPSR1TET2EGLN1 | |
| SCHEMBL6887908 | 0.79 | NPSR1 (0.54) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL17565792 | 0.79 | FFAR3 (0.39) | ALDH1A1 | |
| SCHEMBL2474496 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL4010131 | 0.79 | SMN1; SMN2 (0.30) | MAPTNPSR1 | |
| SCHEMBL11655353 | 0.79 | ALDH1A1 (0.32) | ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432182-A | Inhibitors of gastric acid secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-07-11 | — | — | US | disclosed |
| EP-0330485-B1 | 4-AMINO-3-ACYL QUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC ACID SECRETION | SmithKline Beecham Intercredit B.V. (NL) | 1993-05-26 | — | — | EP | disclosed |
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |
| WO-1989008104-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | disclosed |
| EP-0330485-A1 | 4-Amino-3-acyl quinoline derivatives and their use as inhibitors of gastric acid secretion | SmithKline Beecham Intercredit B.V. (NL) | 1989-08-30 | — | — | EP | disclosed |