Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260448 | 0.95 | BCHE (0.51) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL9269563 | 0.94 | BCHE (0.53) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL9270804 | 0.92 | ACHE (0.49) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL9271362 | 0.92 | BCHE (0.48) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL9269351 | 0.91 | LSS (0.58) | BCHEACHELTA4H | |
| SCHEMBL9273837 | 0.91 | BCHE (0.47) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL9271171 | 0.91 | TSHR (0.55) | TSHRMAPK1BCHEACHELTA4H | |
| SCHEMBL9269010 | 0.91 | BCHE (0.47) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL9266749 | 0.90 | ACHE (0.57) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL9273518 | 0.89 | ACHE (0.47) | NPC1LMNAALOX15TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029155-A1 | NOVEL ANTITUMOUR COMPOUNDS WITH ANTIMITOTIC ACTIVITY | PHARMACIA AB (SE) | 1995-11-02 | — | — | WO | disclosed |