Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NMBR | P28336 | 1/20 | 0.36 |
| ▸ | GRPR | P30550 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270243 | 1.00 | UBE2M (0.47) | UBE2MDCUN1D1KMT2AMEN1LMNA | |
| SCHEMBL9273730 | 0.94 | UBE2M (0.45) | UBE2MDCUN1D1KMT2AMEN1LMNA | |
| SCHEMBL9273736 | 0.94 | UBE2M (0.45) | UBE2MDCUN1D1KMT2AMEN1LMNA | |
| SCHEMBL9266865 | 0.94 | UBE2M (0.45) | UBE2MDCUN1D1KMT2AMEN1LMNA | |
| SCHEMBL9266859 | 0.94 | UBE2M (0.45) | UBE2MDCUN1D1KMT2AMEN1LMNA | |
| SCHEMBL9270860 | 0.90 | UBE2M (0.52) | UBE2MDCUN1D1KMT2AMEN1LMNA | |
| SCHEMBL9270864 | 0.90 | UBE2M (0.52) | UBE2MDCUN1D1KMT2AMEN1LMNA | |
| SCHEMBL9266396 | 0.90 | UBE2M (0.46) | UBE2MDCUN1D1KMT2ALMNAKDM4E | |
| SCHEMBL9266401 | 0.90 | UBE2M (0.46) | UBE2MDCUN1D1KMT2ALMNAKDM4E | |
| SCHEMBL9271741 | 0.88 | NPSR1 (0.39) | KDM4EALDH1A1CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | claimed |
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |