Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 14/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 12/20 | 0.64 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9276974 | 0.96 | AGTR1 (0.62) | AGTR1AGTR2IL4I1 | |
| SCHEMBL9272086 | 0.96 | AGTR1 (0.68) | AGTR1AGTR2IL4I1 | |
| SCHEMBL9275056 | 0.95 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9274124 | 0.95 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9274390 | 0.94 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9271314 | 0.94 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9203926 | 0.93 | AGTR1 (0.70) | AGTR1AGTR2IL4I1 | |
| SCHEMBL9277167 | 0.93 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9272080 | 0.91 | AGTR1 (0.61) | AGTR1AGTR2IL4I1 | |
| Sc-55634 SCHEMBL9202651 | 0.91 | AGTR1 (0.76) | AGTR1AGTR2IL4I1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664803-A1 | N-ARYLHETEROARYLALKYL 1-CYCLOALKYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1995-08-02 | — | — | EP | claimed |
| WO-1994008989-A1 | N-ARYLHETEROARYLALKYL 1-CYCLOALKYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1994-04-28 | — | — | WO | claimed |