Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 10/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269167 | 1.00 | ABCC9 (0.63) | ABCC9ABCB1 | |
| SCHEMBL9274193 | 0.90 | ABCC9 (0.61) | ABCC9ABCB1 | |
| SCHEMBL9270735 | 0.90 | ABCC9 (0.69) | ABCC9ABCB1 | |
| SCHEMBL10888766 | 0.83 | ABCC9 (0.71) | ABCC9ABCB1 | |
| SCHEMBL3298509 | 0.82 | ABCC9 (0.87) | ABCC9ABCB1 | |
| SCHEMBL8342992 | 0.82 | ABCC9 (0.87) | ABCC9ABCB1 | |
| SCHEMBL3298515 | 0.82 | ABCC9 (0.87) | ABCC9ABCB1 | |
| SCHEMBL9218809 | 0.82 | ABCC9 (0.87) | ABCC9ABCB1 | |
| SCHEMBL8343004 | 0.82 | ABCC9 (0.87) | ABCC9ABCB1 | |
| SCHEMBL3298519 | 0.82 | ABCC9 (0.87) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453421-A | Aryl and heterocyclic substituted propenamide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1995-09-26 | — | — | US | claimed |
| EP-0587188-A2 | Aryl and heterocyclic substituted propenamide derivatives | E.R. SQUIBB & SONS, INC. (US) | 1994-03-16 | — | — | EP | claimed |
| JP-6211761-A | — | — | None | — | — | JP | disclosed |
| US-5453421-A | Aryl and heterocyclic substituted propenamide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1995-09-26 | — | — | US | disclosed |
| JP-H06211761-A | ARYL AND HETEROCYCLIC SUBSTITUTED PROPENAMIDE DERIVATIVES | E R SQUIBB & SONS INC | 1994-08-02 | — | — | JP | disclosed |
| EP-0587188-A2 | Aryl and heterocyclic substituted propenamide derivatives | E.R. SQUIBB & SONS, INC. (US) | 1994-03-16 | — | — | EP | disclosed |