Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274089 | 1.00 | NR5A1 (0.56) | NR5A1TP53TSHRPLA2G4BKDM4E | |
| SCHEMBL11311467 | 1.00 | NR5A1 (0.56) | NR5A1TP53TSHRPLA2G4BKDM4E | |
| SCHEMBL11198912 | 1.00 | NR5A1 (0.56) | NR5A1TP53TSHRPLA2G4BKDM4E | |
| SCHEMBL1367833 | 0.95 | SMN1; SMN2 (0.56) | NR5A1TSHRKDM4ECYP1A2CYP2D6 | |
| SCHEMBL910937 | 0.87 | LMNA (0.53) | KDM4ECYP1A2CYP2D6PDE4ASMN1; SMN2 | |
| SCHEMBL9265038 | 0.83 | NR5A1 (0.53) | NR5A1TP53TSHRPLA2G4BSMN1; SMN2 | |
| SCHEMBL11307452 | 0.83 | NR5A1 (0.53) | NR5A1TP53TSHRPLA2G4BSMN1; SMN2 | |
| SCHEMBL7276095 | 0.83 | NR5A1 (0.53) | NR5A1TP53TSHRPLA2G4BSMN1; SMN2 | |
| SCHEMBL11319335 | 0.83 | NR5A1 (0.53) | NR5A1TP53TSHRPLA2G4BSMN1; SMN2 | |
| SCHEMBL11311492 | 0.83 | NR5A1 (0.53) | NR5A1TP53TSHRPLA2G4BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013266-A1 | ACYLPYRROLE-ALKANOIC ACIDS AND INDOLE-2-ALKANOIC ACIDS PLUS THEIR DERIVATIVES FOR USE AS INHIBITORS OF PHOSPHOLIPASE A¿2? | MERCKLE GMBH CHEM.-PHARM. FABRIK (DE) | 1995-05-18 | — | — | WO | disclosed |