Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 2/20 | 0.30 |
| ▸ | NPY2R | P49146 | 2/20 | 0.30 |
| ▸ | NPY4R | P50391 | 2/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112976 | 0.76 | TACR1 (0.42) | TACR1C3AR1NPY1RNPY2RNPY4R | |
| SCHEMBL1389117 | 0.73 | CNR1 (0.41) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL1388296 | 0.72 | TACR1 (0.39) | TACR1C3AR1 | |
| SCHEMBL4651752 | 0.72 | NPY4R (0.41) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL9202531 | 0.72 | MEN1 (0.38) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL8126662 | 0.71 | CNR1 (0.31) | — | |
| SCHEMBL9271799 | 0.71 | CNR1 (0.35) | TACR1C3AR1NPY1RNPY2RNPY4R | |
| SCHEMBL1388355 | 0.70 | TDP1 (0.37) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL9276101 | 0.70 | CNR1 (0.39) | C3AR1NPY1R | |
| SCHEMBL9200886 | 0.69 | TPSAB1 (0.39) | NPY1RNPY2RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |