Phyllodulcin

Phyllodulcin

SCHEMBL92727

COc1ccc([C@H]2Cc3cccc(O)c3C(=O)O2)cc1O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.57
TP53 P04637 2/20 0.57
CYP3A4 P08684 2/20 0.57
XDH P47989 2/20 0.57
CYP1A1 P04798 2/20 0.57
CYP1A2 P05177 2/20 0.57
CYP1B1 Q16678 2/20 0.57
MAPT P10636 1/20 0.57
HPGD P15428 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
PKM P14618 1/20 0.57
NPC1 O15118 1/20 0.57
CA12 O43570 1/20 0.57
KDM1A O60341 1/20 0.57
ALDH1A1 P00352 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
TSHR P16473 1/20 0.57
CA4 P22748 1/20 0.57
DPP4 P27487 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phyllodulcin SCHEMBL30401623 1.00 CYP19A1 (0.57) CYP19A1TP53CYP3A4XDHCYP1A1
Phyllodulcin SCHEMBL12205057 1.00 CYP19A1 (0.57) CYP19A1TP53CYP3A4XDHCYP1A1
Phyllodulcin SCHEMBL30460064 1.00 CYP19A1 (0.57) CYP19A1TP53CYP3A4XDHCYP1A1
Phyllodulcin SCHEMBL12205058 1.00 CYP19A1 (0.57) CYP19A1TP53CYP3A4XDHCYP1A1
Phyllodulcin SCHEMBL1505793 0.93 CYP19A1 (0.51) CYP19A1TP53CYP3A4XDHCYP1A1
SCHEMBL30873044 0.93 MAOA (0.52) CYP19A1TP53CYP3A4XDHCYP1A1
SCHEMBL11525073 0.93 MAOA (0.52) CYP19A1TP53CYP3A4XDHCYP1A1
SCHEMBL31028365 0.90 POLB (0.57) CYP19A1CYP1A1CYP1A2CYP1B1MAOA
Thunberginol E SCHEMBL23699014 0.87 CYP19A1 (0.68) CYP19A1TP53CYP3A4XDHCYP1A1
Thunberginol E SCHEMBL29366907 0.87 CYP19A1 (0.68) CYP19A1TP53CYP3A4XDHCYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3974 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3487318-B1 GLUCOSYRINGIC ACID ANALOGS AS SWEETNESS PROFILE MODIFIERS PEPSICO INC (US) 2026-04-01 EP claimed
US-20260009063-A1 HIGH-PURITY STEVIOL GLYCOSIDES PURECIRCLE SDN BHD (MY) 2026-01-08 US claimed
EP-4658090-A1 SIAMENOSIDE I SWEETENED BEVERAGES WITH MOGROSIDE BLENDS The Coca-Cola Company (US) 2025-12-10 EP claimed
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP claimed
EP-4655386-A1 GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF CARBON-CONTAINING NON-NITROGEN COMPOUNDS Fertis India Pvt Ltd (IN) 2025-12-03 EP claimed
EP-4190172-B1 SWEETENER COMPOSITION COMPRISING STEVIOL GLYCOSIDE SWEETENERS WITH IMPROVED FLAVOR PROFILES COCA COLA CO (US) 2025-11-26 EP claimed
US-20250351855-A1 TASTE OF CONSUMABLES THE PRODUCT MAKERS (AUSTRALIA) PTY LTD (AU) 2025-11-20 US claimed
WO-2025202907-A1 SWEETENER COMPOSITION FOR POUCHED ORAL PRODUCTS Nicoventures Trading Limited (GB) 2025-10-02 WO claimed
EP-4623708-A1 SWEETENER COMPOSITION FOR POUCHED ORAL PRODUCTS Nicoventures Trading Limited (GB) 2025-10-01 EP claimed
US-12427120-B2 Compositions comprising guaifenesin and flavour compounds containing an isovanillyl group SYMRISE AG (DE) 2025-09-30 US claimed
EP-1384475-A1 LIVER FUNCION PROTECTING OR AMELIORATING AGENT KYOWA HAKKO KOGYO CO., LTD. (JP) 2004-01-28 EP claimed
WO-2003103415-A1 NOVEL SWEETENER COMPOSITIONS AND METHODS OF USE ALLEN ANN DE WEES (US) 2003-12-18 WO claimed
CN-1457782-A Dry spaxxacin suspension agent for resisting bacterial infection and its preparing method HONGYI SCIENCE AND TECHNOLOGY (CN) 2003-11-26 CN claimed
CN-1444940-A Cresol powder with dissolution increased and its preparing method-analgesic, antipyretic and anti-inflammatory agent HONGYI SCIENCE AND TECHNOLOGY (CN) 2003-10-01 CN claimed
CN-1443535-A Tegasevod maleate oral preparation and its preparation process-for curing intestinal irritability syndrome NANCHANG HONGYI SCIENCE & TECH (CN) 2003-09-24 CN claimed
CN-1439373-A Oral preparation of mehanesulfonae pezusacine and its preparing process-antiinfection HONGYI SCIENCE & TECHNOLOGY CO (CN) 2003-09-03 CN claimed
CN-1439363-A Dichloroacetic acid diisopropylamine oral preparation and its preparation process-treatment of liver function injury HONGYI SCIENCE & TECHNOLOGY CO (CN) 2003-09-03 CN claimed
EP-1317915-A1 HAIR NOURISHMENTS AND METHOD OF SCREENING THE SAME SHISEIDO COMPANY, LTD. (JP) 2003-06-11 EP claimed
EP-0785251-A2 Spirit base, its preparation and its use in the preparation of spirits OKA, s.r.o. (CZ) 1997-07-23 EP claimed
US-4171430-A CHROMATOGRAPHY TOYO SODA MANUFACTURING CO., LTD. (JP) 1979-10-16 US claimed