Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CPS1 | P31327 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 2/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273051 | 1.00 | MEN1 (0.52) | MEN1KMT2ACPS1RAB9AALDH1A1 | |
| SCHEMBL9269186 | 0.80 | DCUN1D1 (0.46) | ALDH1A1SMN1; SMN2UBE2MDCUN1D1 | |
| SCHEMBL9269180 | 0.80 | DCUN1D1 (0.46) | ALDH1A1SMN1; SMN2UBE2MDCUN1D1 | |
| SCHEMBL9269097 | 0.79 | DCUN1D1 (0.48) | UBE2MDCUN1D1 | |
| SCHEMBL9267487 | 0.78 | DCUN1D1 (0.43) | ALDH1A1TP53UBE2MDCUN1D1 | |
| SCHEMBL9267491 | 0.78 | DCUN1D1 (0.43) | ALDH1A1TP53UBE2MDCUN1D1 | |
| SCHEMBL9267290 | 0.77 | DCUN1D1 (0.48) | UBE2MDCUN1D1 | |
| SCHEMBL9267293 | 0.77 | DCUN1D1 (0.48) | UBE2MDCUN1D1 | |
| SCHEMBL9272164 | 0.77 | UBE2M (0.42) | UBE2MDCUN1D1 | |
| SCHEMBL9272166 | 0.77 | UBE2M (0.42) | UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |