SCHEMBL9273288

SCHEMBL9273288

C/C(=N\O)c1ccc(S(=O)(=O)c2cc([C@@]3(O)CCO[C@@H](C)C3)cs2)cc1CC#N

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9273965 0.86
SCHEMBL9048977 0.84 ALOX5 (0.41) ALOX5
SCHEMBL9283872 0.84
SCHEMBL9267479 0.83 ALOX5 (0.42) ALOX5
SCHEMBL9267466 0.83 ALOX5 (0.42) ALOX5
SCHEMBL9267473 0.83 ALOX5 (0.42) ALOX5
SCHEMBL9273269 0.81 ALOX5 (0.36) ALOX5
SCHEMBL9075180 0.80 ALOX5 (0.43) ALOX5
SCHEMBL9047697 0.79 ALOX5 (0.63) ALOX5
SCHEMBL9275318 0.76 ALOX5 (0.41) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0681576-A1 OXIME DERIVATIVES ZENECA LIMITED (GB) 1995-11-15 EP claimed
WO-1994017054-A1 OXIME DERIVATIVES ZENECA LIMITED (GB) 1994-08-04 WO claimed
EP-0681576-A1 OXIME DERIVATIVES ZENECA LIMITED (GB) 1995-11-15 EP disclosed
WO-1994017054-A1 OXIME DERIVATIVES ZENECA LIMITED (GB) 1994-08-04 WO disclosed