Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | HPGD | P15428 | 1/20 | 0.82 |
| ▸ | ADAMTS5 | Q9UNA0 | 6/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273340 | 0.98 | KMT2A (0.84) | KMT2AHPGDADAMTS5NPC1RAB9A | |
| SCHEMBL9263432 | 0.93 | KMT2A (0.75) | KMT2AHPGDADAMTS5NPC1RAB9A | |
| SCHEMBL9271168 | 0.91 | KMT2A (0.73) | KMT2AHPGDADAMTS5NPC1RAB9A | |
| SCHEMBL9271728 | 0.91 | KMT2A (0.73) | KMT2AHPGDADAMTS5NPC1RAB9A | |
| SCHEMBL5272168 | 0.90 | KMT2A (1.00) | KMT2AHPGDRAB9ASMN1; SMN2CYP2C19 | |
| SCHEMBL9268569 | 0.90 | ADAMTS5 (0.78) | KMT2AHPGDADAMTS5NPC1RAB9A | |
| SCHEMBL9272176 | 0.90 | ADAMTS5 (0.78) | KMT2AHPGDADAMTS5NPC1RAB9A | |
| SCHEMBL9271748 | 0.88 | KMT2A (0.82) | KMT2AHPGDADAMTS5SMN1; SMN2CYP2C19 | |
| SCHEMBL9272482 | 0.87 | SRC (0.69) | KMT2AHPGDADAMTS5NPC1RAB9A | |
| SCHEMBL9274804 | 0.87 | KMT2A (0.66) | KMT2AHPGDADAMTS5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029155-A1 | NOVEL ANTITUMOUR COMPOUNDS WITH ANTIMITOTIC ACTIVITY | PHARMACIA AB (SE) | 1995-11-02 | — | — | WO | disclosed |