Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573216 | 0.87 | NR1H4 (0.45) | NAMPTPTGDR2NR1H4FFAR1KDM4E | |
| SCHEMBL23099401 | 0.84 | MALT1 (0.48) | MALT1BCHENAMPTIDO1DDB1 | |
| SCHEMBL8785537 | 0.84 | CA2 (0.54) | NAMPTIDO1ALDH1A1LMNAMEN1 | |
| SCHEMBL7203913 | 0.84 | MALT1 (0.59) | MALT1BCHENAMPTIDO1MEN1 | |
| SCHEMBL22419858 | 0.83 | MALT1 (0.49) | MALT1BCHENAMPTIDO1NR1H4 | |
| SCHEMBL22644748 | 0.82 | MALT1 (0.51) | MALT1BCHENAMPTIDO1PTPN11 | |
| SCHEMBL22645024 | 0.82 | NAMPT (0.49) | MALT1BCHENAMPTIDO1DDB1 | |
| SCHEMBL8785731 | 0.82 | CA1 (0.52) | NAMPTIDO1POLBALDH1A1MEN1 | |
| SCHEMBL4899444 | 0.82 | MALT1 (0.54) | MALT1BCHENAMPTIDO1PTPN11 | |
| SCHEMBL16935831 | 0.81 | MALT1 (0.50) | MALT1BCHENAMPTIDO1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033724-A1 | PHENETHANOLAMINE DERIVATIVES AND THEIR USE AS ATYPICAL BETA-ADRENOCEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |