SCHEMBL927367

SCHEMBL927367

CCC(NCCN(C)C)OCCNC

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.45
CARM1 Q86X55 1/20 0.45
PRMT6 Q96LA8 1/20 0.45
PRMT1 Q99873 1/20 0.45
PRMT8 Q9NR22 1/20 0.45
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2196022 0.68 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL48539 0.66
SCHEMBL17383867 0.66 PRMT3 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL3421349 0.65 HTR1D (0.32)
SCHEMBL18427004 0.65 TDP1 (0.44) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL30783028 0.63
SCHEMBL2236546 0.63
Ammonia Solution, Strong SCHEMBL19410298 0.63
Hydrochloric Acid SCHEMBL3855671 0.63 PRMT3 (0.93) PRMT3CARM1PRMT6PRMT1PRMT8
Hydrochloric Acid SCHEMBL3610130 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009512-A1 REDUCTION OF ALDEHYDES IN AMINES HUNTSMAN PETROCHEMICAL LLC (US) 2011-01-13 US disclosed
EP-2257592-A2 REDUCTION OF ALDEHYDES IN AMINES Huntsman Petrochemical LLC (US) 2010-12-08 EP disclosed
WO-2009117479-A2 REDUCTION OF ALDEHYDES IN AMINES HUNTSMAN PETROCHEMICAL CORPORATION (US) 2009-09-24 WO disclosed