Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 12/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530291 | 0.89 | ERCC1 (0.45) | GPR34FOLH1ERCC1ERCC4FFAR1 | |
| SCHEMBL6065430 | 0.81 | MME (0.58) | FOLH1MME | |
| SCHEMBL6716497 | 0.81 | MME (0.58) | FOLH1MME | |
| SCHEMBL11346818 | 0.81 | MME (0.58) | FOLH1MME | |
| SCHEMBL121370 | 0.81 | MME (0.58) | FOLH1MME | |
| SCHEMBL121371 | 0.81 | MME (0.58) | FOLH1MME | |
| SCHEMBL8414223 | 0.80 | FOLH1 (0.55) | FOLH1MME | |
| SCHEMBL148423 | 0.80 | FOLH1 (0.55) | FOLH1MME | |
| SCHEMBL8121226 | 0.80 | ERCC1 (0.43) | GPR34FOLH1ERCC1ERCC4 | |
| SCHEMBL34461699 | 0.79 | FOLH1 (0.55) | GPR34FOLH1ERCC1ERCC4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |