Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 2/20 | 0.40 |
| ▸ | MC1R | Q01726 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273671 | 0.89 | GPR34 (0.50) | ERCC1ERCC4FOLH1GPR34FFAR1 | |
| Trifluoroacetic Acid SCHEMBL8138243 | 0.83 | F2 (0.42) | ERCC1ERCC4FOLH1GPR34FFAR1 | |
| SCHEMBL20362252 | 0.81 | ACE (0.51) | MEP1B | |
| SCHEMBL18375339 | 0.81 | ACE (0.51) | MEP1B | |
| SCHEMBL7354256 | 0.80 | EPHX1 (0.46) | ERCC1ERCC4FOLH1EPHX1DPP7 | |
| SCHEMBL7354251 | 0.80 | EPHX1 (0.46) | ERCC1ERCC4FOLH1EPHX1DPP7 | |
| SCHEMBL8112583 | 0.79 | ERCC1 (0.50) | ERCC1ERCC4FOLH1DPP7KLKB1 | |
| SCHEMBL6163777 | 0.78 | CNR1 (0.47) | FOLH1EPHX1DPP7NLRP3MAPK8 | |
| SCHEMBL8121226 | 0.76 | ERCC1 (0.43) | ERCC1ERCC4FOLH1GPR34 | |
| SCHEMBL8803839 | 0.75 | MAOB (0.52) | ERCC1ERCC4EPHX1DPP7VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |
| US-5616620-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-04-01 | — | — | US | disclosed |