Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45262 | 0.87 | — | — | |
| 1,3-Butanediol SCHEMBL3960533 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPK1TSHR | |
| SCHEMBL3192047 | 0.84 | — | — | |
| Ethylene Glycol SCHEMBL27534184 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TSHR | |
| SCHEMBL28997335 | 0.84 | — | — | |
| Water SCHEMBL5885198 | 0.84 | — | — | |
| SCHEMBL15287147 | 0.84 | — | — | |
| SCHEMBL11208790 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL28414432 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| 1,3-Propanediol SCHEMBL332299 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500443-B1 | Phenylethanolamino- and phenylethanolaminomethyltetralines, process for their preparation, intermediates of this process and pharmaceutical compositions containing them | SANOFI SA (FR) | 1995-04-26 | — | — | EP | disclosed |
| EP-0500443-A1 | Phenylethanolamino- and phenylethanolaminomethyltetralines, process for their preparation, intermediates of this process and pharmaceutical compositions containing them | SANOFI (FR) | 1992-08-26 | — | — | EP | disclosed |
| EP-0499755-A1 | Phenylethanolaminotetralines, process for their preparation, intermediates of this process and pharmaceutical compositions containing them | MIDY S.p.A. (IT) | 1992-08-26 | — | — | EP | disclosed |