Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 10/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.51 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14544900 | 1.00 | HMGCR (0.52) | HMGCRCYP2C9SIRT6ABCC3ABCB11 | |
| SCHEMBL4020685 | 1.00 | HMGCR (0.52) | HMGCRCYP2C9SIRT6ABCC3ABCB11 | |
| SCHEMBL4901682 | 1.00 | HMGCR (0.52) | HMGCRCYP2C9SIRT6ABCC3ABCB11 | |
| SCHEMBL4901679 | 1.00 | HMGCR (0.52) | HMGCRCYP2C9SIRT6ABCC3ABCB11 | |
| SCHEMBL4020679 | 1.00 | HMGCR (0.52) | HMGCRCYP2C9SIRT6ABCC3ABCB11 | |
| SCHEMBL16476432 | 0.92 | HMGCR (0.43) | HMGCR | |
| SCHEMBL9763505 | 0.91 | HMGCR (0.52) | HMGCR | |
| SCHEMBL1660810 | 0.91 | HMGCR (0.52) | HMGCR | |
| SCHEMBL9763539 | 0.91 | HMGCR (0.52) | HMGCR | |
| SCHEMBL5597970 | 0.91 | HMGCR (0.52) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379917-B1 | Optically active (meth)acrylic-acid derivatives, their preparation, their polymerisation into optically active polymers and their use | BAYER AG (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5274167-A | A N-(meth)acryloyl amino acid amide | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0379917-A2 | Optically active (meth)acrylic-acid derivatives, their preparation, their polymerisation into optically active polymers and their use | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |