Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 9/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763870 | 1.00 | HMGCR (0.52) | HMGCR | |
| SCHEMBL1660811 | 1.00 | HMGCR (0.52) | HMGCR | |
| SCHEMBL9763505 | 1.00 | HMGCR (0.52) | HMGCR | |
| SCHEMBL5597970 | 1.00 | HMGCR (0.52) | HMGCR | |
| SCHEMBL9763877 | 1.00 | HMGCR (0.52) | HMGCR | |
| SCHEMBL1660810 | 1.00 | HMGCR (0.52) | HMGCR | |
| SCHEMBL4901679 | 0.91 | HMGCR (0.52) | HMGCR | |
| SCHEMBL4020685 | 0.91 | HMGCR (0.52) | HMGCR | |
| SCHEMBL14544900 | 0.91 | HMGCR (0.52) | HMGCR | |
| SCHEMBL9274196 | 0.91 | HMGCR (0.52) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004747-A | Isoquinolinones | MAY & BAKER LIMITED (GB) | 1991-04-02 | — | — | US | claimed |
| US-5004747-A | Isoquinolinones | MAY & BAKER LIMITED (GB) | 1991-04-02 | — | — | US | disclosed |