Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 19/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264106 | 0.81 | ADRB2 (0.73) | ADRB2ADRB3ADRB1 | |
| SCHEMBL9268240 | 0.79 | ADRB2 (1.00) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7714872 | 0.79 | ADRB3 (0.73) | ADRB2ADRB3ADRB1 | |
| SCHEMBL9268335 | 0.78 | ADRB3 (1.00) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7708588 | 0.78 | ADRB3 (0.77) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7708585 | 0.78 | ADRB3 (0.77) | ADRB2ADRB3ADRB1 | |
| SCHEMBL9267558 | 0.77 | ADRB3 (0.73) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL7717196 | 0.77 | ADRB3 (0.63) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL7714620 | 0.76 | ADRB3 (0.74) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL7712899 | 0.76 | ADRB3 (0.74) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033724-A1 | PHENETHANOLAMINE DERIVATIVES AND THEIR USE AS ATYPICAL BETA-ADRENOCEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |