Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594059 | 0.98 | CARM1 (0.46) | CARM1PRMT6PRMT8HRH3CACNA2D1 | |
| SCHEMBL22790763 | 0.87 | CACNA2D1 (0.47) | CARM1PRMT6PRMT8HRH3CACNA2D1 | |
| SCHEMBL26352150 | 0.85 | HRH3 (0.48) | CARM1PRMT6PRMT8HRH3CACNA2D1 | |
| SCHEMBL28642601 | 0.84 | PAOX (0.33) | CARM1PRMT6PRMT8 | |
| SCHEMBL9276057 | 0.83 | CACNA2D1 (0.43) | CARM1PRMT6PRMT8HRH3CACNA2D1 | |
| SCHEMBL12342813 | 0.81 | ALDH1A1 (0.41) | — | |
| SCHEMBL21025308 | 0.81 | CHRM5 (0.41) | — | |
| SCHEMBL21730467 | 0.80 | CARM1 (0.41) | CARM1PRMT6PRMT8HRH3CACNA2D1 | |
| SCHEMBL8557028 | 0.79 | CARM1 (0.55) | CARM1PRMT6PRMT8HRH3 | |
| SCHEMBL8557026 | 0.79 | CARM1 (0.55) | CARM1PRMT6PRMT8HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |