SCHEMBL9274607

SCHEMBL9274607

O=C(Nc1cccc(Cl)c1Cl)c1ccc(O)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.72
KMT2A Q03164 5/20 0.72
MAPT P10636 4/20 0.72
NPC1 O15118 4/20 0.72
RAB9A P51151 4/20 0.72
LMNA P02545 3/20 0.72
HPGD P15428 1/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
TRPV1 Q8NER1 1/20 0.54
TP53 P04637 1/20 0.53
ALDH1A1 P00352 2/20 0.53
GLA P06280 1/20 0.53
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KDM4E B2RXH2 1/20 0.51
MAPK1 P28482 1/20 0.50
POLB P06746 1/20 0.50
ESR1 P03372 1/20 0.49
ESRRG P62508 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL11148558 0.98 MEN1 (0.70) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11148551 0.98 MEN1 (0.70) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL28577755 0.86 NPC1 (0.73) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL9621459 0.86 MEN1 (0.82) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11305208 0.85 NPC1 (0.77) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11310396 0.85 MEN1 (0.70) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL28583973 0.84 MAPT (0.88) KMT2AMAPTNPC1RAB9ALMNA
SCHEMBL28589236 0.84 MAPT (0.58) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL7296261 0.83 RAB9A (0.78) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11303001 0.83 KMT2A (0.67) MEN1KMT2AMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300454-B1 BENZAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PLANT GROWTH REGULANT HODOGAYA CHEMICAL CO., LTD. (JP) 1992-01-15 EP claimed
EP-0300454-A2 Benzamide derivative, process for its production and plant growth regulant HODOGAYA CHEMICAL CO., LTD. (JP) 1989-01-25 EP claimed
JP-56156247-A None JP disclosed
JP-1139557-A None JP disclosed
JP-1029348-A None JP disclosed
JP-56083467-A None JP disclosed
JP-7224019-A None JP disclosed
JP-7224018-A None JP disclosed
JP-56156255-A None JP disclosed
JP-56156251-A None JP disclosed
JP-H07224019-A PRODUCTION OF 2',3'-DICHLORO-3-ETHOXYMETHOXYBENZANILIDE HODOGAYA CHEM CO LTD 1995-08-22 JP disclosed
US-4878942-A AND HERBICIDE HODOGAYA CHEMICAL CO., LTD. (JP) 1989-11-07 US disclosed
JP-H01139557-A BENZAMIDE DERIVATIVE HODOGAYA CHEM CO LTD 1989-06-01 JP disclosed
JP-S6429348-A BENZAMIDE DERIVATIVE HODOGAYA CHEMICAL CO LTD 1989-01-31 JP disclosed
EP-0300454-A2 Benzamide derivative, process for its production and plant growth regulant HODOGAYA CHEMICAL CO., LTD. (JP) 1989-01-25 EP disclosed
US-4385927-A ETHER OF N-2,3-DICHLOROPHENYL P-HYDROXYBENZAMIDE HODOGAYA CHEMICAL CO., LTD. (JP) 1983-05-31 US disclosed
JP-S56156251-A BENZAMIDE DERIVATIVE AND HERBICIDE COMPRISING IT HODOGAYA CHEM CO LTD 1981-12-02 JP disclosed
JP-S56156247-A BENZAMIDE DERIVATIVE AND HERBICIDE COMPRISING IT HODOGAYA CHEM CO LTD 1981-12-02 JP disclosed
JP-S56156255-A BENZAMIDE DERIVATIVE AND HERBICIDE COMPRISING IT HODOGAYA CHEM CO LTD 1981-12-02 JP disclosed
JP-S5683467-A BENZAMIDE DERIVATIVE AND HERBICIDE CONTAINING THE SAME HODOGAYA CHEM CO LTD 1981-07-08 JP disclosed