Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.56 |
| ▸ | DPP4 | P27487 | 6/20 | 0.56 |
| ▸ | IDH1 | O75874 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274740 | 1.00 | PTPN1 (0.56) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7183852 | 0.93 | PTPN1 (0.64) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7183855 | 0.93 | PTPN1 (0.64) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7177534 | 0.91 | PTPN1 (0.66) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7177537 | 0.91 | PTPN1 (0.66) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7185991 | 0.86 | PTPN1 (0.56) | PTPN1DPP4ABCG2CTSLCTSB | |
| SCHEMBL7185985 | 0.86 | PTPN1 (0.56) | PTPN1DPP4ABCG2CTSLCTSB | |
| SCHEMBL7187188 | 0.86 | PTPN1 (0.76) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7177521 | 0.86 | PTPN1 (0.59) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7187194 | 0.86 | PTPN1 (0.76) | PTPN1DPP4IDH1ABCB1UGT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |