Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 4/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275156 | 1.00 | UBE2M (0.50) | UBE2MDCUN1D1LPAR1MEN1KMT2A | |
| SCHEMBL9272153 | 0.94 | UBE2M (0.49) | UBE2MDCUN1D1LPAR1MEN1KMT2A | |
| SCHEMBL9272160 | 0.94 | UBE2M (0.49) | UBE2MDCUN1D1LPAR1MEN1KMT2A | |
| SCHEMBL9274371 | 0.94 | UBE2M (0.52) | UBE2MDCUN1D1LPAR1ALDH1A1KDM4E | |
| SCHEMBL9265896 | 0.94 | UBE2M (0.52) | UBE2MDCUN1D1LPAR1ALDH1A1KDM4E | |
| SCHEMBL9265902 | 0.94 | UBE2M (0.52) | UBE2MDCUN1D1LPAR1ALDH1A1KDM4E | |
| SCHEMBL9274224 | 0.87 | UBE2M (0.51) | UBE2MDCUN1D1LPAR1MAPT | |
| SCHEMBL9274219 | 0.87 | UBE2M (0.51) | UBE2MDCUN1D1LPAR1MAPT | |
| SCHEMBL9275098 | 0.86 | UBE2M (0.55) | UBE2MDCUN1D1KMT2ALMNA | |
| SCHEMBL9275100 | 0.86 | UBE2M (0.55) | UBE2MDCUN1D1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |