Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272302 | 0.88 | LMNA (0.43) | LMNAPTPN1CDC25BAKT1TOP2A | |
| SCHEMBL9266301 | 0.82 | LMNA (0.52) | LMNAPTPN1CDC25BAKT1L3MBTL1 | |
| SCHEMBL21218543 | 0.82 | LMNA (0.52) | LMNAPTPN1CDC25BAKT1L3MBTL1 | |
| SCHEMBL9343457 | 0.79 | LMNA (0.39) | LMNAPTPN1CDC25BL3MBTL1TAAR1 | |
| SCHEMBL9287478 | 0.79 | TOP2A (0.39) | TOP2AHMGCRHDAC1HDAC2HDAC6 | |
| SCHEMBL477836 | 0.78 | TAAR1 (0.41) | LMNATAAR1HRH4HRH3 | |
| SCHEMBL6282511 | 0.76 | LMNA (0.55) | LMNAPTPN1CDC25BAKT1 | |
| SCHEMBL9267781 | 0.76 | LMNA (0.55) | LMNAPTPN1CDC25BAKT1 | |
| SCHEMBL10024055 | 0.76 | HMGCR (0.37) | TOP2AHMGCRHDAC1HDAC2HDAC6 | |
| SCHEMBL3142790 | 0.76 | LMNA (0.63) | LMNAPTPN1CDC25BAKT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5443970-A | SEPARATION OF ISOMERS IN A MIXTURE BY SELECTIVE REACTION | ZENECA LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |