Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275429 | 0.84 | NPC1 (0.47) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30885597 | 0.83 | NPC1 (0.60) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL387104 | 0.81 | GAA (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL29410009 | 0.79 | NPC1 (0.61) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30250143 | 0.76 | NPC1 (0.49) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL19400301 | 0.76 | NPC1 (0.51) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28330431 | 0.76 | LMNA (0.64) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9275433 | 0.73 | NPC1 (0.49) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6680571 | 0.73 | NPC1 (0.72) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13273290 | 0.72 | MAPT (0.45) | RAB9ANPC1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074980-A2 | METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISORDERS AND LIVER DISORDERS USING INDANE ACETIC ACID DERIVATIVES | DARA BIOSCIENCES, INC. (US) | 2012-06-07 | — | — | WO | disclosed |