Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 14/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275938 | 1.00 | ADRB3 (0.47) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL9271270 | 0.85 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9271276 | 0.85 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9275631 | 0.82 | ADRB3 (0.57) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9275635 | 0.82 | ADRB3 (0.57) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9264106 | 0.80 | ADRB2 (0.73) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9264110 | 0.70 | ADRB3 (0.44) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL9272088 | 0.66 | PTGDR2 (0.37) | — | |
| SCHEMBL9271485 | 0.66 | ADRB3 (0.72) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9271478 | 0.66 | ADRB3 (0.72) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033724-A1 | PHENETHANOLAMINE DERIVATIVES AND THEIR USE AS ATYPICAL BETA-ADRENOCEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |