Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106444 | 0.87 | HRH3 (0.51) | OPRK1OPRM1OPRD1HRH3CYP2D6 | |
| SCHEMBL9102325 | 0.84 | MAPT (0.46) | — | |
| SCHEMBL9103007 | 0.84 | CHRNA1 (0.48) | — | |
| SCHEMBL9103021 | 0.84 | CHRNA1 (0.48) | — | |
| SCHEMBL9102341 | 0.84 | MAPT (0.46) | — | |
| SCHEMBL9103858 | 0.84 | MAPT (0.43) | — | |
| SCHEMBL9103848 | 0.84 | MAPT (0.43) | — | |
| SCHEMBL9103996 | 0.83 | OPRK1 (0.47) | OPRK1OPRM1OPRD1HRH3CYP2D6 | |
| SCHEMBL9101356 | 0.83 | HRH3 (0.44) | OPRK1OPRM1OPRD1HRH3CYP2D6 | |
| SCHEMBL9102911 | 0.83 | HRH3 (0.44) | OPRK1OPRM1OPRD1HRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |