SCHEMBL9276281

SCHEMBL9276281

[c]1cc[c]c(/N=N/c2ccccc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
MEN1 O00255 7/20 0.39
KMT2A Q03164 7/20 0.39
MAPT P10636 7/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 3/20 0.39
PKM P14618 2/20 0.39
HTT P42858 2/20 0.39
TDP1 Q9NUW8 5/20 0.35
MAPK1 P28482 4/20 0.35
HSD17B10 Q99714 2/20 0.35
TSHR P16473 2/20 0.35
TRPA1 O75762 2/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
CYP2D6 P10635 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10353577 0.82
SCHEMBL672173 0.77 ALDH1A1 (0.55) ALDH1A1MEN1KMT2AMAPTNPC1
SCHEMBL1225987 0.77 ALDH1A1 (0.55) ALDH1A1MEN1KMT2AMAPTNPC1
Azobenzene SCHEMBL28190808 0.72 ALDH1A1 (0.92) ALDH1A1MEN1KMT2AMAPTNPC1
Azobenzene SCHEMBL28862110 0.72 ALDH1A1 (0.92) ALDH1A1MEN1KMT2AMAPTNPC1
SCHEMBL148167 0.71 ALDH1A1 (0.67) ALDH1A1MEN1KMT2AMAPTNPC1
SCHEMBL148166 0.71 ALDH1A1 (0.67) ALDH1A1MEN1KMT2AMAPTNPC1
SCHEMBL22637422 0.71 ALDH1A1 (0.67) ALDH1A1MEN1KMT2AMAPTNPC1
SCHEMBL3188806 0.71 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AMAPTNPC1
Azobenzene SCHEMBL16697676 0.69 ALDH1A1 (0.86) ALDH1A1MEN1KMT2AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4056523-A SULFONAMIDO SUBSTITUTED HOECHST AKTIENGESELLSCHAFT (DT) 1977-11-01 US claimed
US-3979386-A YELLOW, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1976-09-07 US claimed
US-5408021-A Used in the fabrication of polymeric films for second order nonlinear optics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-04-18 US disclosed
EP-0560914-B1 HYBRID OPTICAL WAVEGUIDES FOR PHASE-MATCHED NONLINEAR WAVELENGTH CONVERSION DU PONT (US) 1995-03-08 EP disclosed
EP-0560909-B1 POLYMERIC FILMS FOR SECOND ORDER NONLINEAR OPTICS DU PONT (US) 1994-11-23 EP disclosed
US-5294493-A Multilayer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-15 US disclosed
EP-0560909-A1 POLYMERIC FILMS FOR SECOND ORDER NONLINEAR OPTICS. DU PONT (US) 1993-09-22 EP disclosed
EP-0560914-A1 HYBRID OPTICAL WAVEGUIDES FOR PHASE-MATCHED NONLINEAR WAVELENGTH CONVERSION. DU PONT (US) 1993-09-22 EP disclosed
US-5155791-A HYBRID OPTICAL WAVEGUIDES FOR PHASE-MATCHED NONLINEAR WAVELENGTH CONVERSION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-13 US disclosed
WO-1992010781-A1 POLYMERIC FILMS FOR SECOND ORDER NONLINEAR OPTICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO disclosed
WO-1992010782-A1 HYBRID OPTICAL WAVEGUIDES FOR PHASE-MATCHED NONLINEAR WAVELENGTH CONVERSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO disclosed
US-4116959-A ISOINDOLINE PIGMENTS CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4052410-A YELLOW, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1977-10-04 US disclosed
US-3979386-A YELLOW, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1976-09-07 US disclosed
US-3883504-A Water-insoluble carbonylalkylene sulfonamido containing azo dyestuffs HOECHST AG 1975-05-13 US disclosed