Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2039820 | 1.00 | ADORA2B (0.42) | ADORA2BLMNASMN1; SMN2ADORA2AACHE | |
| SCHEMBL28454 | 1.00 | ADORA2B (0.42) | ADORA2BLMNASMN1; SMN2ADORA2AACHE | |
| SCHEMBL9279475 | 1.00 | ADORA2B (0.42) | ADORA2BLMNASMN1; SMN2ADORA2AACHE | |
| SCHEMBL8804033 | 1.00 | ADORA2B (0.42) | ADORA2BLMNASMN1; SMN2ADORA2AACHE | |
| SCHEMBL9389745 | 0.94 | ADORA2B (0.42) | ADORA2BLMNASMN1; SMN2ADORA2AACHE | |
| SCHEMBL8978234 | 0.91 | ADORA2B (0.41) | ADORA2BLMNASMN1; SMN2ADORA2AACHE | |
| SCHEMBL2733652 | 0.91 | ADORA2B (0.42) | ADORA2BLMNASMN1; SMN2ADORA2AACHE | |
| SCHEMBL9284660 | 0.90 | ADORA2B (0.40) | ADORA2BLMNASMN1; SMN2ADORA2AACHE | |
| SCHEMBL9385319 | 0.84 | ADORA2B (0.41) | ADORA2BLMNASMN1; SMN2ADORA2AACHE | |
| SCHEMBL21708442 | 0.83 | ADORA2B (0.45) | ADORA2BLMNASMN1; SMN2ADORA2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013808-A1 | METHOD FOR SELECTIVELY INHIBITING IL-2 SIGNAL TRANSDUCTION | CELL THERAPEUTICS, INC. (US) | 1995-05-26 | — | — | WO | disclosed |
| WO-1994022863-A9 | SECOND MESSENGER CELL SIGNALING INHIBITORS | — | 1994-12-22 | — | — | WO | disclosed |