SCHEMBL9280211

SCHEMBL9280211

C=Cc1ccc(-c2ccccc2)c(C=C)c1.C=Cc1ccc(C)c(C)c1C=C

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.33
MCL1 Q07820 1/20 0.33
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258568 0.82 ALDH1A1 (0.44) ESR2MCL1TP53TDP1ALDH1A1
SCHEMBL158243 0.75 KDM4E (0.31) ALDH1A1
SCHEMBL29434185 0.75 KDM4E (0.31) ALDH1A1
SCHEMBL8758668 0.74 ESR2 (0.53) ESR2TP53TDP1ALDH1A1TSHR
Naphthalene SCHEMBL1712201 0.74 CYP2A6 (0.41) TDP1ALDH1A1TSHRCYP1A2
SCHEMBL7569813 0.72 ALDH1A1 (0.44) MCL1TP53TDP1ALDH1A1TSHR
SCHEMBL11019624 0.71 ALDH1A1 (0.40) MCL1TDP1ALDH1A1TSHR
SCHEMBL31432621 0.70 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL8848267 0.70 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL9127978 0.70 BACE1 (0.43) TP53TDP1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5430086-A Rubber composition for tire treads SUMITOMO RUBBER INDUSTRIES (JP) 1995-07-04 US disclosed