Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31224147 | 1.00 | PDE4A (0.39) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL18825609 | 0.86 | USP2 (0.48) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL29159266 | 0.86 | USP2 (0.48) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL9763747 | 0.86 | USP2 (0.48) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL1949269 | 0.81 | PDE4A (0.37) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL7534971 | 0.80 | PDE4A (0.39) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL3646782 | 0.78 | LMNA (0.33) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL6753289 | 0.77 | PDE4A (0.41) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL4280412 | 0.76 | PDE4A (0.37) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL9312516 | 0.76 | TSHR (0.38) | PDE4ALMNAUSP2SLCO1B1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422602-B2 | Methods and compositions for determining nucleic acid degradation | BIO-RAD LABORATORIES, INC. (US) | 2016-08-23 | — | — | US | claimed |
| US-20140051595-A1 | Methods and Compositions for Determining Nucleic Acid Degradation | BIO-RAD LABORATORIES, INC. (US) | 2014-02-20 | — | — | US | claimed |
| US-9422602-B2 | Methods and compositions for determining nucleic acid degradation | BIO-RAD LABORATORIES, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20140051595-A1 | Methods and Compositions for Determining Nucleic Acid Degradation | BIO-RAD LABORATORIES, INC. (US) | 2014-02-20 | — | — | US | disclosed |
| US-5403711-A | Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1995-04-04 | — | — | US | disclosed |
| EP-0365627-B1 | CATALYTIC HYBRIDIZATION SYSTEMS FOR THE DETECTION OF NUCLEIC ACID SEQUENCES BASED ON THEIR ACTIVITY AS COFACTORS IN CATALYTIC REACTIONS IN WHICH A COMPLEMENTARY LABELED NUCLEIC ACID PROBE IS CLEAVED | UNIV IOWA RES FOUND (US) | 1993-12-22 | — | — | EP | disclosed |
| EP-0365627-A4 | CATALYTIC HYBRIDIZATION SYSTEMS FOR THE DETECTION OF NUCLEIC ACID SEQUENCES BASED ON THEIR ACTIVITY AS COFACTORS IN CATALYTIC REACTIONS IN WHICH A COMPLEMENTARY LABELED NUCLEIC ACID PROBE IS CLEAVED | — | 1990-10-10 | — | — | EP | disclosed |
| EP-0365627-A1 | CATALYTIC HYBRIDIZATION SYSTEMS FOR THE DETECTION OF NUCLEIC ACID SEQUENCES BASED ON THEIR ACTIVITY AS COFACTORS IN CATALYTIC REACTIONS IN WHICH A COMPLEMENTARY LABELED NUCLEIC ACID PROBE IS CLEAVED. | UNIV IOWA RES FOUND (US) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989009284-A1 | CATALYTIC HYBRIDIZATION SYSTEMS FOR THE DETECTION OF NUCLEIC ACID SEQUENCES BASED ON THEIR ACTIVITY AS COFACTORS IN CATALYTIC REACTIONS IN WHICH A COMPLEMENTARY LABELED NUCLEIC ACID PROBE IS CLEAVED | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1989-10-05 | — | — | WO | disclosed |