SCHEMBL9280398

SCHEMBL9280398

CCCCc1cn(-c2ccccc2Cl)c(=O)n1CCc1ccc(-c2ccccc2-c2nnn[nH]2)nc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 13/20 0.54
AGTR2 P50052 12/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7679757 0.93 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL9283900 0.92 AGTR1 (0.64) AGTR1AGTR2
SCHEMBL9283499 0.91 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL9285919 0.89 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL9273358 0.88 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL9289867 0.87 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL9283917 0.86 AGTR1 (0.48) AGTR1AGTR2
SCHEMBL9288220 0.85 AGTR1 (0.57) AGTR1AGTR2
SCHEMBL7684790 0.85 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL8109564 0.85 AGTR1 (0.74) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0664802-A1 N-ARYLHETEROARYLALKYL 1-PHENYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1995-08-02 EP claimed
EP-0664802-A1 N-ARYLHETEROARYLALKYL 1-PHENYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1995-08-02 EP disclosed