Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160215 | 0.96 | TSHR (0.69) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL5157954 | 0.90 | ALDH1A1 (0.67) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL30173476 | 0.85 | TSHR (0.78) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL3805742 | 0.85 | TSHR (0.78) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL9636466 | 0.84 | ALDH1A1 (0.79) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL5515133 | 0.84 | ALDH1A1 (0.79) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL12816232 | 0.84 | ALDH1A1 (0.79) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL7078029 | 0.84 | ALDH1A1 (0.79) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL2853795 | 0.84 | ALDH1A1 (0.79) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL17961072 | 0.84 | ALDH1A1 (0.79) | TSHRMAPK1CYP3A4TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478808-A | Blood disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |