Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Bisphenol A. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.76 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.76 |
| ▸ | ESRRG | P62508 | 5/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.76 |
| ▸ | AR | P10275 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.76 |
| ▸ | HTR6 | P50406 | 1/20 | 0.76 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bisphenol A SCHEMBL29411202 | 1.00 | ESR1 (0.76) | ESR1ESR2ESRRGCYP3A4AR | |
| Bisphenol A SCHEMBL1610311 | 0.92 | ESR1 (0.73) | ESR1ESR2ESRRGCYP3A4AR | |
| Bisphenol A SCHEMBL30912031 | 0.91 | ESR1 (0.70) | ESR1ESR2ESRRGCYP3A4AR | |
| Bisphenol A SCHEMBL17728808 | 0.88 | ESR1 (0.73) | ESR1ESR2ESRRGCYP3A4AR | |
| Bisphenol A SCHEMBL28408194 | 0.88 | ESR1 (0.68) | ESR1ESR2ESRRGCYP3A4AR | |
| Bisphenol A SCHEMBL5049892 | 0.88 | ESR1 (0.59) | ESR1ESR2ESRRGCYP3A4AR | |
| Bisphenol A SCHEMBL8058731 | 0.87 | ESR1 (1.00) | ESR1ESR2ESRRGCYP3A4AR | |
| Bisphenol A SCHEMBL15062 | 0.87 | ESR1 (1.00) | ESR1ESR2ESRRGCYP3A4AR | |
| SCHEMBL27996 | 0.87 | ESR1 (1.00) | ESR1ESR2ESRRGCYP3A4AR | |
| SCHEMBL15868669 | 0.87 | ESR1 (1.00) | ESR1ESR2ESRRGCYP3A4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119822682-A | Multi-effect stabilizer and preparation method and application thereof | 湖南中天凿岩科技有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-118772636-A | Biaxially oriented polyimide film, flame-retardant thermosetting adhesive tape for vehicle and application | 太仓金煜电子材料有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118755224-A | Low-smoke halogen-free flame-retardant elastomer material and preparation method thereof | 浙江元通线缆制造有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-118620357-A | PBAT degradable membrane material and preparation method thereof | 江苏恒凌奇科技有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-116096822-B | Release coating composition | 东丽尖端素材株式会社 | 2024-05-31 | — | — | CN | claimed |
| CN-116096822-A | Release coating composition | 东丽尖端素材株式会社 | 2023-05-09 | — | — | CN | claimed |
| CN-120923869-A | Formula and production process of PVC composite stabilizer with ageing resistance | 德阳鑫金府塑胶有限公司 | 2025-11-11 | — | — | CN | disclosed |
| US-20250136748-A1 | CATIONICALLY POLYMERIZABLE FLAME RETARDANT COMPOSITIONS | DELO INDUSTRIE KLEBSTOFFE GMBH & CO. KGAA (DE) | 2025-05-01 | — | — | US | disclosed |
| CN-119822682-A | Multi-effect stabilizer and preparation method and application thereof | 湖南中天凿岩科技有限公司 | 2025-04-15 | — | — | CN | disclosed |
| EP-4473049-A1 | CATIONICALLY POLYMERISABLE FLAME-RETARDANT MATERIALS | DELO Industrie Klebstoffe GmbH & Co. KGaA (DE) | 2024-12-11 | — | — | EP | disclosed |
| CN-118772636-A | Biaxially oriented polyimide film, flame-retardant thermosetting adhesive tape for vehicle and application | 太仓金煜电子材料有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118755224-A | Low-smoke halogen-free flame-retardant elastomer material and preparation method thereof | 浙江元通线缆制造有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-118647661-A | Cationic polymerizable flame retardant materials | 德路工业胶粘剂有限两合公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-116096822-A | Release coating composition | 东丽尖端素材株式会社 | 2023-05-09 | — | — | CN | disclosed |
| CN-115819944-A | Easily-demoulded flame-retardant polycarbonate composition | 江苏金发科技新材料有限公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4126810-A1 | USE OF SUBSTITUTED CINNAMIC ACID ESTERS AS STABILISERS FOR ORGANIC MATERIALS, STABILISED ORGANIC MATERIAL, METHOD FOR STABILISING ORGANIC MATERIALS AND SPECIFIC CINAMIC ACID ESTERS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2023-02-08 | — | — | EP | disclosed |
| CN-115073988-A | Primer, coating agent set, cured product, and laminate | 荒川化学工业株式会社 | 2022-09-20 | — | — | CN | disclosed |
| CN-114075388-A | Thermosetting release coating agent, cured product, thermosetting release film, and method for producing same | 荒川化学工业株式会社 | 2022-02-22 | — | — | CN | disclosed |
| CN-112080045-B | Covering rubber for carborundum composite conveyor belt and super-wear-resistant diamond-steel-grit rubber conveyor belt | 浙江奋飞橡塑制品有限公司 | 2022-02-18 | — | — | CN | disclosed |
| US-5408280-A | Process for rendering contact lenses hydrophilic | CIBA-GEIGY CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |