Aniline

Aniline

SCHEMBL9282904

CCCCCS(=O)(=O)O.Nc1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.43
S1PR1 P21453 1/20 0.43
S1PR3 Q99500 1/20 0.43
MMP1 P03956 1/20 0.43
MMP9 P14780 1/20 0.43
MMP13 P45452 1/20 0.43
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
NAAA Q02083 1/20 0.40
CYP2D6 P10635 1/20 0.40
EPHX2 P34913 1/20 0.40
TSHR P16473 1/20 0.39
ALDH1A1 P00352 3/20 0.39
HTT P42858 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
EPHX1 P07099 3/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL8010474 0.87 TSHR (0.44) S1PR2S1PR1S1PR3CA12CA9
SCHEMBL11513473 0.85 CYP2D6 (0.49) S1PR2S1PR1S1PR3CA12CA9
Toluene SCHEMBL11498470 0.84 CA12 (0.42) S1PR2S1PR1S1PR3MMP1MMP9
Biphenyl SCHEMBL27876466 0.84 PTPN1 (0.48) S1PR2S1PR1S1PR3NAAAEPHX2
Phenol SCHEMBL27982105 0.84 ESR1 (0.45) S1PR2S1PR1S1PR3MMP1MMP9
Benzene SCHEMBL28758814 0.82 EPHX2 (0.51) S1PR2S1PR1S1PR3EPHX2TSHR
Benzene SCHEMBL11150225 0.82 EPHX2 (0.51) S1PR2S1PR1S1PR3EPHX2TSHR
Benzene SCHEMBL27649746 0.82 EPHX2 (0.51) S1PR2S1PR1S1PR3EPHX2TSHR
Aniline SCHEMBL10806060 0.82 TSHR (0.52) CYP2D6TSHRALDH1A1TDP1MAPT
Benzene SCHEMBL27649739 0.82 EPHX2 (0.51) S1PR2S1PR1S1PR3EPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5380456-A Aromatic aminosulfonic acid, liquid bleach UNITED STATES BORAX & CHEMICAL CORPORATION (US) 1995-01-10 US disclosed
EP-0466902-A4 STABILIZATION OF AQUEOUS PEROXYGEN SOLUTIONS 1992-05-20 EP disclosed
EP-0466902-A1 STABILIZATION OF AQUEOUS SOLUTIONS CONTAINING SODIUM PERBORATE OR SODIUM PERCARBONATE UNITED STATES BORAX & CHEMICAL CORPORATION (US) 1992-01-22 EP disclosed
WO-1991011388-A1 STABILIZATION OF AQUEOUS PEROXYGEN SOLUTIONS UNITED STATES BORAX & CHEMICAL CORPORATION (US) 1991-08-08 WO disclosed