Aniline

Aniline

SCHEMBL8010474

CCCS(=O)(=O)O.Nc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
CYP2D6 P10635 1/20 0.43
GAA P10253 3/20 0.40
ALDH1A1 P00352 3/20 0.39
NT5E P21589 1/20 0.39
PSIP1 O75475 1/20 0.39
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PKM P14618 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
S1PR2 O95136 1/20 0.36
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516364 0.90 CYP2D6 (0.52) TSHRCYP2D6GAAALDH1A1NT5E
Aniline SCHEMBL10806060 0.87 TSHR (0.52) TSHRCYP2D6GAAALDH1A1NT5E
Aniline SCHEMBL9282904 0.87 S1PR2 (0.43) TSHRCYP2D6ALDH1A1TDP1CA12
SCHEMBL11515446 0.86 ALDH1A1 (0.50) TSHRCYP2D6ALDH1A1HSD17B10TDP1
Aniline SCHEMBL27650765 0.85 TSHR (0.50) TSHRCYP2D6GAAALDH1A1NT5E
Aniline SCHEMBL27616266 0.84 KDM4E (0.42) TSHRALDH1A1HSD17B10TDP1CA12
Phenol SCHEMBL17102999 0.82 CA12 (0.46) TSHRGAAALDH1A1PSIP1HSD17B10
Toluene SCHEMBL28166100 0.82 LMNA (0.46) TSHRGAAALDH1A1PSIP1TDP1
Chlorobenzene SCHEMBL27670059 0.82 TSHR (0.46) TSHRGAAALDH1A1PSIP1NPSR1
Naphthalene SCHEMBL30775918 0.81 GAA (0.43) TSHRGAAALDH1A1PSIP1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117813500-A Optical detection chip and optical detection system 公立大学法人北九州市立大学 2024-04-02 CN disclosed
US-6146847-A INTRODUCING FOREIGN DNA INTO CELL; CONTACTING BEFORE, DURING, OR AFTER WITH BIOCOMPATIBLE EXPRESSION ENHANCING AGENT WHICH IS NOT BUTYRATE OR BUTYRIC ACID; MAINTAINING IN NON-SELECTIVE MEDIUM; AFTER 5 DAYS, DETECTING FOREIGN PROTEIN GENESPAN CORPORATION (US) 2000-11-14 US disclosed